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GNF-5 is a selective allosteric inhibitor of Bcr-Abl (IC50 = 220 nM for wild-type Abl)
with antineoplastic activity
Meisoindigo has been a routine therapeutic agent in the clinical treatment of chronic myelogenous leukemia (CML) in China since the 1980s
the activities of CYP3A4
HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal–regulated kinase 1 (ERK1)
BI-187004 - CAS# 1303515-32-3 Catalog No.:M11474-10 GNF-5 is a selective allostericBI 187004, also known as VTP 34072, is an 11 hydroxysteroid dehydrogenase 1 inhibitor. BI187004 VTP 34072 is being studied for the treatment of type 2 diabetes and metabolic syndrome. In preclinical studies, BI187004 VTP 34072 had a positive impact on multiple cardiovascular and metabolic risk factors associated with metabolic syndrome, which differentiates it from other classes of type 2 diabetes drugs. Product information CAS Number: 1303515 32 3
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