Adagrasib Catalog No.:M12926-2 Smiles: CC(C)(O)C1=CC2=NC(=NC(=C2S1)N1CCOCC1)C1C=NC(N)=NC=1

Smiles: CC(C)(O)C1=CC2=NC(=NC(=C2S1)N1CCOCC1)C1C=NC(N)=NC=1

VE-821 is the first highly selective and potent ATR inhibitor

16(14):2257-63

and normalizes tumor-associated vasculature in the Calu-6 non–small cell lung xenograft model

Formula: C18H11Cl2NO4

Adagrasib Catalog No.:M12926-2 Smiles: CC(C)(O)C1=CC2=NC(=NC(=C2S1)N1CCOCC1)C1C=NC(N)=NC=1Adagrasib (MRTX849) is a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug like properties, selectively modifies mutant cysteine 12 in GDP bound KRASG12C and inhibits KRAS dependent signaling. Product information CAS Number: 2326521 71 3 Molecular Weight: 604. 12 Formula: C32H35ClFN7O2 Synonym: MRTX849 Chemical Name: 2 ((S) 4 (7 (8 chloronaphthalen 1 yl) 2 (((S) 1 methylpyrrolidin 2 yl)methoxy) 5, 6, 7, 8