Thalidomide-PEG2-C2-NH2 Catalog No.:M13080-2 SHP2 Inhibition Prevents Adaptive Resistance

SHP2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple Cancer Models

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PDK4-IN-1 shows good bioavailability (64%)

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Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma

Thalidomide-PEG2-C2-NH2 Catalog No.:M13080-2 SHP2 Inhibition Prevents Adaptive ResistanceThalidomide PEG2 C2 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and 2 unit PEG linker used in PROTAC technology. Product information CAS Number: 2093416 32 9 Molecular Weight: 404. 42 Formula: C19H24N4O6 Chemical Name: 4 ({2 [2 (2 aminoethoxy)ethoxy]ethyl}amino) 2 (2,6 dioxopiperidin 3 yl) 2,3 dihydro 1H isoindole 1,3 dione Smiles: NCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O