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GSK3α/GSK3β at Ser21/Ser9 and Foxo-1/3a at Thr24/Thr32
BMS-986242 is more prone to oxidative metabolism and less susceptible to glucuronidation
The oral bioavailability of Trimethobenzamide is 60% to 100%
9-10H2/b2-1+/t17-
InChiKey: LGGHDPFKSSRQNS-UHFFFAOYSA-N
Quassin (hemihydrate) GSK3α/GSK3β at Ser21/Ser9 and Foxo-1/3aQuassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0. 15 M. Quassin possesses reversible antifertility, anti estrogenic and anti plasmodial activity. Product information CAS Number: 76 78 8 Molecular Weight: 388. 45 Formula: C22H28O6 Chemical Name: (3aR, 3a1S, 6aR, 7aS, 8S, 11aS, 11bS) 2, 10 dimethoxy 3, 3a1, 8, 11a tetramethyl 3a, 4, 6a, 7, 7a, 8, 11a, 11b