Midostaurin-D5 569Tocopherol S(+)-Efonidipine blocks L-type and T-type

S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels

It also antagonizes head twitches and increases frequency of spontaneous excitatory postsynaptic currents in brain slices

Pillarsetty NV

GSK 2118436B

3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide

Midostaurin-D5 569Tocopherol S(+)-Efonidipine blocks L-type and T-typeMidostaurin D5 (PKC412 D5) is a deuterium labeled Midostaurin. Midostaurin is a multi targeted protein kinase inhibitor which inhibits PKC , Syk, Flk 1, Akt, PKA, c Kit, c Fgr, c Src, FLT3, PDFR and VEGFR1 2 with IC50s ranging from 22 500 nM. Product information Molecular Weight: 575. 67 Formula: C35H30N4O4 Chemical Name: N [(2S,3R,4R,6R) 6 hydrogenio 3 methoxy 2 methyl 16 oxo 29 oxa 1,7,17 triazaoctacyclo[12. 12. 2. 1,. 0,. 0,. 0,. 0,. 0,]nonacosa