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PF-04856264 892al-Glu(OSu)-OH Deoxypodophyllotoxin evokes increase of intracellular

SKU: 3363302316

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Description

Deoxypodophyllotoxin evokes increase of intracellular Ca2+ concentrations in DRG neurons

It works as an insulin sensitizer

1'-biphenyl]-4-yl]carbamoyl}amino)methyl]phenyl}acetic acid

N=C1SC2CCCCC=2N1CC(=O)C1C=CC(=CC=1)[N+]([O-])=O

6-difluorophenyl)methyl]-2-[4-(2-methylpropanamido)phenyl]-4-oxo-4H

PF-04856264 892al-Glu(OSu)-OH Deoxypodophyllotoxin evokes increase of intracellularPF 04856264 is a potent and selective Nav1. 7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1. 7, respectively. PF 04856264 has low potency against the rat Nav1. 7 channel. PF 04856264 shows analgesic effect. Product information CAS Number: 1235397 05 3 Molecular Weight: 437. 49 Formula: C20H15N5O3S2 Chemical Name: 3 cyano 4 [2 (1 methyl 1H pyrazol 5 yl)phenoxy] N (1,3 thiazol 2 yl)benzene 1 sulfonamide

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