CuATSM l-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside 22)23/h1-7

22)23/h1-7

1H3/b20-18+

Formula: C23H28ClFN4O2

PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively

6-dimethylphenyl)methyl]amino}-N-(2-hydroxyethyl)-2

CuATSM l-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside 22)23/h1-7CuATSM is a highly potent radical trapping antioxidant (RTA) and inhibitor of (phospho)lipid peroxidation, thereby accounting for its (their) ability to inhibit ferroptosis. The metallo protein Cu Zn superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic