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Smiles: CC1=NC2=CC(F)=C(F)C=C2N1C1=CN=CC(NC2C=CC(=CC=2)C(F)(F)F)=N1
1993 Dec 1
and RAD140 also has good bioavailability in rats (F = 27-63%) and monkeys (65-75%)
Formula: C20H20ClN3O2
Riociguat constitutes the first drug of a novel class of sGC stimulators
CL-82198 ent antioxidant with anticancer activities Smiles: CC1=NC2=CC(F)=C(F)C=C2N1C1=CN=CC(NC2C=CC(=CC=2)C(F)(F)F)=N1CL 82198 is a selective inhibitor of MMP 13. CL 82198 binds to the entire S1 pocket of MMP 13, which is the basis for its selectivity towards MMP 13 and the lack of inhibitory activities against other MMPs. CL 82198 is a pharmacologic treatment for preventing osteoarthritis (OA) progression. Product information CAS Number: 307002 71 7 Molecular Weight: 338. 83 Formula: C17H23ClN2O3 Chemical Name: N [4 (morpholin 4 yl)butyl] 1 benzofuran 2 carboxamide