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Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice
the rate-limiting enzyme involved in the conversion of nicotinamide into nicotinamide adenine dinucleotide (NAD)
Smiles: CN1CCN(CC1)C1=CC=C(C=C1NC(=O)C1=CNC(=O)C=C1C(F)(F)F)C1=CC(CN2CCOCC2)=CC=C1
4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2
Crenolanib inhibits [125I]-IAAP photocrosslinking of ABCB1 at high concentrations
YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 Differential effects between γ-secretase inhibitorsYM 155, CAS No. 781661 94 7, is a novel survivin suppressant with an IC50 of 0. 54 nM for the inhibition of survivin promoter activity. Sepantronium bromide, also known as YM 155, is a small molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and
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