Belzutifan 292rctigenin 4'-O-β-gentiobioside 2-dihydropyridine-3-amido]benzoic acid

2-dihydropyridine-3-amido]benzoic acid

Guochao Lin

NC[C@@H](F)CP(O)=O

an effective AR inhibitor

also known as Homo-PROTAC

Belzutifan 292rctigenin 4'-O-β-gentiobioside 2-dihydropyridine-3-amido]benzoic acidBelzutifan (PT2977) is an orally active and selective HIF 2 inhibitor with an IC50 of 9 nM. Belzutifan, as a second generation HIF 2 inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC). Product information CAS Number: 1672668 24 4 Molecular Weight: 383. 34 Formula: C17H12F3NO4S Chemical Name: 3 {[(1S,2S,3R) 2,3 difluoro 1 hydroxy 7 methanesulfonyl 2,3