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Smiles: O=C(NC1CC1)C1C=C(ON=1)C1=CC=CS1
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ZOL administration prevented osteolysis and significantly reduced the amount of OS-induced bone formation while has no effect on tumor burden at the primary site
1'-biphenyl]-2-carboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide
30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP
Manidipine dihydrochloride D7545 Smiles: O=C(NC1CC1)C1C=C(ON=1)C1=CC=CS1Manidipine dihydrochloride (CV 4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2. 6 nM. IC50 value: 2. 6 nM Target: calcium channel Manidipine dihydrochloride is described to block T type Ca2+ channels specifically and is also described to have a high selectivity for the vasculature, presenting negligible cardiodepression as compared to other Ca2+ channel antagonists. Manidipine is also described to not
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