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(Z)-Mirin Size:Contact [email protected] for quotation Small-molecule activation of neuronal cell

SKU: 36942446891

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Description

Small-molecule activation of neuronal cell fate

CAS Number: 3818-50-6

Smiles: OC(=O)CCCCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

is a RORγt agonist

orally active and dual TLR7/8 inhibitor with IC50s of 11

(Z)-Mirin Size:Contact [email protected] for quotation Small-molecule activation of neuronal cellMirin is a small molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Target: in vitro: Mirin was shown to block Mre11 exonuclease activity and MRN dependent ATM activation, and to inhibit the ionizing radiation induced G2 M checkpoint and homologous recombination in mammalian cells. Mirin inhibition of ATM activation is independent of Mre11 nuclease inhibition since the M(HN)RN and M(HL DV)RN mutant complexes are inhibited equivalently to the

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