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Ticlopidine Hydrochloride AS inhibitor PubMed Central PMCID: PMC4741963

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Description

PubMed Central PMCID: PMC4741963

CAS Number: 82854-37-3

InChiKey: NEXGBSJERNQRSV-UHFFFAOYSA-N

Its depletion of intracellular Ca 2+ stores may be linked to the induction of apoptosis

Research results suggest that KU-55933 may be a novel chemotherapeutic agent targeting cancer resistant to traditional chemotherapy or immunotherapy due to aberrant activation of Akt

Ticlopidine Hydrochloride AS inhibitor PubMed Central PMCID: PMC4741963Ticlopidine is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. Research initially showed that it was useful for preventing strokes and coronary stent occlusions. However, because of its rare but serious side effects of neutropenia and thrombotic thrombocytopenic purpura it was primarily used in patients in whom aspirin was not tolerated, or in whom dual antiplatelet therapy was desirable.

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