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It inhibits metastasis in an MHCC97-H mouse xenograft model but does not reduce tumor growth
NC1C=CN([C@H]2C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])([O-])=O)O2)C(=O)N=1
InChiKey: SLJKKTFIAUAYGR-UHFFFAOYSA-N
4-triazol-5-yl)ethyl]-4-[1-[6-(trifluoromethyl)pyridin-3-yl]cyclopropyl]-1H-pyrrole-2-carboxamide
CAS Number: 941690-55-7
TAK-828F strel It inhibits metastasis in anTAK 828F is a potent, selective, and orally available retinoic acid receptor related orphan receptor t (RORt) inverse agonist (binding IC50=1. 9 nM, reporter gene IC50=6. 1 nM). TAK 828F shows excellent RORt isoforms selectivity (>5000 fold selectivity against human ROR and ROR). Product information CAS Number: 1854901 94 2 Molecular Weight: 509. 57 Formula: C28H32FN3O5 Chemical Name: 2 {3 [(5R) 5 [(7 fluoro 1,1 dimethyl 2,3 dihydro 1H inden 5
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