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4 nM for CDK4/D1 and CDK6/D1
Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL
L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic
with Kis of 11
GSK369796 Dihydrochloride can also inhibit hERG potassium ion channel repolarization with an IC50 of 7
Gefitinib impurity 2 Catalog No.:M31681-C 4 nM for CDK4/D1 andGefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY 50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 246512 44 7 Molecular
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