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with mean decreases of 2
2016 Oct 20
is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM)
10% Tween 80
[3H]-basimglurant saturation analysis on recombinant human mGlu5 reveals monophasic saturation isotherms with Kd of 1
UK-5099 - CAS# 56396-35-1 66052 with mean decreases of 2UK 5099, CAS No. 56396 35 1, is a specific and potent mitochondrial pyruvate carrier blocker (MCK blocker). The UK5099 treated cells showed significantly higher proportion of side population (SP) fraction and expressed higher levels of stemness markers Oct3 4 and Nanog. Chemosensitivity examinations revealed that the UK5099 treated cells became more resistant to chemotherapy compared to the non treated cells. MPC blocker (UK5099) application may be an