JWG-071 hibitor and a 25-fold increase in

and a 25-fold increase in GBM cell apoptosis in vivo

17-trimethyl-1

Chemical Name: 4-carbamothioylphenyl 2-(6-methoxynaphthalen-2-yl)propanoate

2018 Jan 4

HS-173 clearly suppresses the expression of p-Akt and p-P70S6K along with decreasing expression of collagen I and vimentin in the mice with CCl4-induced liver fibrosis

JWG-071 hibitor and a 25-fold increase inJWG 071 is the first reported kinase selective chemical probe for ERK5. JWG 071 improves ERK5 activity and BRD4 selectivity. JWG 071 will be a much needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology. Product information CAS Number: 2250323 50 1 Molecular Weight: 612. 76 Formula: C34H44N8O3 Chemical Name: 2 (butan 2 yl) 5 ({2 methoxy 4 [4 (4 methylpiperazin 1 yl)piperidine 1 carbonyl]phenyl}amino) 9 methyl 2, 4, 6, 9 tetraazatricyclo[9.