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InChi: InChI=1S/C28H22Cl4N2O2/c29-22-8-6-18(12-24(22)31)10-20-15-34(28(36)26(33)14-17-4-2-1-3-5-17)16-21(27(20)35)11-19-7-9-23(30)25(32)13-19/h1-13
shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR
106(33):14132-7
as a near-infrared fluorescent probe
¹³]tetracos-15-ene-2
PXS-5153A monohydrochloride 5041 InChi: InChI=1S/C28H22Cl4N2O2/c29-22-8-6-18(12-24(22)31)10-20-15-34(28(36)26(33)14-17-4-2-1-3-5-17)16-21(27(20)35)11-19-7-9-23(30)25(32)13-19/h1-13PXS 5153A monohydrochloride is a potent, selective, orally active and fast acting lysyl oxidase like 2 3 enzymatic (LOXL2 LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS 5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. Product information Molecular Weight: 438. 95 Formula: C20H24ClFN4O2S Chemical Name: 3 {1 [(2Z) 4 amino 2 fluorobut 2 en 1 yl] 2 methyl