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Treatment with Danusertib results in an increase in p53 protein levels and an associated increase in p21 protein
3R)-2-((S)-1-((S)-2-((S)-6-amino-2-((S)-1-((S)-2-amino-5-(diaminomethyleneamino)pentanoyl)pyrrolidine-2-carboxamido)hexanamido)-5-(diaminomethyleneamino)pentanoyl)pyrrolidine-2-carboxamido)-3-hydroxybutanamido)-3-hydroxybutanamido)-4-methylpentanamido)succinamide 2
CAS Number: 1158264-69-7
is structurally related to MGCD-265 (Glesatinib)
irreversible and broad spectrum caspase inhibitor
Quinolinic acid ycycline monohydrate Treatment with Danusertib results inQuinolinic acid is an endogenous N methyl D aspartate (NMDA) receptor agonist synthesized from L tryptophan via the kynurenine pathway and thereby has the potential of mediating N methyl D aspartate neuronal damage and dysfunction. Product information CAS Number: 89 00 9 Molecular Weight: 167. 12 Formula: C7H5NO4 Chemical Name: pyridine 2,3 dicarboxylic acid Smiles: OC(=O)C1=CC=CN=C1C(O)=O InChiKey: GJAWHXHKYYXBSV UHFFFAOYSA N InChi: InChI=1S C7H5NO4
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