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(241):77-83
1155/2015/813816
targeting Smoothened (Smo) with an EC50 ~1 nM
Molecular Weight: 439
Chemical Name: 1-methyl-D-tryptophan
Enzastaurin - CAS# 170364-57-5 0280 (241):77-83Enzastaurin, CAS No. 170364 57 5, also known as DB 102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) stimulated neo angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Product information CAS Number:
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