EGFR-IN-7 3-C2-NH-Boc 77 μM and more than

77 μM and more than 100-fold selectivity over other GRKs

4-dihydroxyphenyl)-2-hydroxypropanoate

2018 Jan 19

increased caspase-3 and appearance of increased nuclear size

and active against the human A2780 ovarian carcinoma implanted sc in nude mice

EGFR-IN-7 3-C2-NH-Boc 77 μM and more thanEGFR IN 7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7. 92 nM and 0. 218 nM for EGFR (WT) and EGFR (mutant C797S T790M L858R) respectively, and shows anti tumor activity. Product information CAS Number: 2267329 76 8 Molecular Weight: 694. 60 Formula: C32H41BrN9O2P Chemical Name: 5 bromo N4 [5 (dimethylphosphoryl)quinoxalin 6 yl] N2 {2 methoxy 5 methyl 4 [4 (4 methylpiperazin 1