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4-dihydroisoquinolin-2(1 h)-yl)methanone
Formula: C18H13BrN4O
SCH 51344 was effective in inhibiting the anchorage-independent growth of Rat-2 fibroblast cells transformed by the three forms of oncogenic RAS and RAC V12
a New Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibitor
30-16-/t17-
Solamargine - CAS# 20311-51-7 Catalog No.:M9872-10 4-dihydroisoquinolin-2(1 h)-yl)methanoneSolamargine is a glycoalkaloid that has been found in S. lycocarpum and has anticancer activity. It decreases viability of H1650, H1975, PC 9, A549, and H1299 non small cell lung cancer (NSCLC) cells. Solamargine increases ERK1 2 phosphorylation and decreases the expression of DNA methyltranferase 1 (DNMT1) in H1299 and A549 cells. It reduces tumor growth and increases ERK1 2 phosphorylation and reduces the expression of the prostaglandin E2 receptor,
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