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PI3Kα/mTOR-IN-1 Catalog No.:M18955-C 11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9

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Description

11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9

PNU-288034 is metabolically stable in liver microsomes across species

InChi: InChI=1S/C21H19Cl2N5O2/c1-13(21-17(22)10-24-11-18(21)23)30-15-3-5-20-16(8-15)19(26-27-20)4-2-14-9-25-28(12-14)6-7-29/h2-5

InChi: InChI=1S/C26H23BrFN7O3/c1-14(36)25-19-8-16(17-10-29-15(2)30-11-17)6-7-20(19)35(33-25)13-24(37)34-12-18(28)9-21(34)26(38)32-23-5-3-4-22(27)31-23/h3-8

Formula: C32H38ClNO12

PI3Kα/mTOR-IN-1 Catalog No.:M18955-C 11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9PI3K mTOR IN 1 is a potent PI3K mTOR dual inhibitor, with an IC50 of 7 nM for PI3K in a cell assay, and Kis of 10. 6 nM and 12. 5 nM for mTOR and PI3K in a cell free assay , respectively. Product information CAS Number: 1013098 90 2 Molecular Weight: 310. 35 Formula: C16H18N6O Chemical Name: 2 amino 8 cyclopentyl 4 methyl 6 (1H pyrazol 4 yl) 7H,8H pyrido[2,3 d]pyrimidin 7 one Smiles: CC1N=C(N)N=C2C=1C=C(C(=O)N2C1CCCC1)C1=CNN=C1 InChiKey:

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