FLLL32 xizine dihydrochloride 7 nM) and IL-1b induced

7 nM) and IL-1b induced IL-6 (IC5050=1

56(3):322-4

17-trioxa-11-azapentacyclo[16

E3 ligase Ligand 3

Smiles: CSC1=CC=C(CN2CC(CCC2)NC2C=C3C=NNC3=CC=2)C=C1

FLLL32 xizine dihydrochloride 7 nM) and IL-1b inducedFLLL32, a synthetic analog of curcumina, is a JAK2 STAT3 dual inhibitor with anti tumor activity. FLLL32 can inhibit the induction of STAT3 phosphorylation by IFN and IL 6 in breast cancer cells. Product information CAS Number: 1226895 15 3 Molecular Weight: 464. 55 Formula: C28H32O6 Chemical Name: (2E) 3 (3, 4 dimethoxyphenyl) 1 {1 [(2E) 3 (3, 4 dimethoxyphenyl)prop 2 enoyl]cyclohexyl}prop 2 en 1 one Smiles: COC1=CC( C=C C(=O)C2(CCCCC2)C(=O) C=C