SR-18292 iguanide Isosilybin A is able to

Isosilybin A is able to significantly activate PPARγ at a concentration of 30 μM (2

with a Ki of <1 nM

PARP1-IN-5 dihydrochloride can upregulate the expression of γ-H2AX and decrease the expression of PAR

18-9-5-3-6-10-18)19-11-7-4-8-12-19

2)3)64-41-38(58)35(55)32(52)26(19-49)61-41/h10

SR-18292 iguanide Isosilybin A is able toSR 18292 is a PPAR gamma coactivator 1 (PGC 1) inhibitor, which increases PGC 1 acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes. Product information CAS Number: 2095432 55 4 Molecular Weight: 366. 50 Formula: C23H30N2O2 Chemical Name: 1 {tert butyl[(4 methylphenyl)methyl]amino} 3 (1H indol 4 yloxy)propan 2 ol Smiles: CC1C=CC(CN(CC(O)COC2=CC=CC3NC=CC=32)C(C)(C)C)=CC=1 InChiKey: BNRANURXPKRRKP