4'-bromo-Resveratrol - CAS# 1224713-90-9 92 hydrochloride 24 hours) treatment suppresses the

24 hours) treatment suppresses the proliferation of both WI38 VA13 and IMR90 cells in a dose-dependent manner

Asciminib is undergoing clinical development testing in patients with CML and Philadelphia chromosome-positive acute lymphoblastic leukaemia

MP-470 also binds to and inhibits several c-Kit mutants

31)26-22-13-24-28(25-22)19-5-3-6-19/h2

CAS Number: 1893-33-0

4'-bromo-Resveratrol - CAS# 1224713-90-9 92 hydrochloride 24 hours) treatment suppresses the4' bromo Resveratrol is a Sirt1 and Sirt3 inhibitor. Sirtuins are protein deacetylases regulating aging processes and many physiological functions. Resveratrol activates human Sirt1 and inhibits Sirt3, and can mimic calorie restriction effects including lifespan extension in lower organisms. In vitro: Sirtuin modulation was studied by using 4 bromo resveratrol in a previous study. 4 bromo Resveratrol inhibited Sirt3 with much higher potency than