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GDC-0941 was used at 1-10 µM in vitro and in cellular assays
is a cell-permeable Stat3 inhibitor that binds to the Stat3-SH2 domain
Chemical Name: 2-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide
It has >100-fold selectivity over other methyltransferases and other non-epigenetic targets
5-dimethylbenzamide
5-Hydroxymethyldeoxyuridine - CAS# 5116-24-5 180 GDC-0941 was used at 1-105 Hydroxymethyldeoxyuridine, CAS No. 5116 24 5, is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8. 5 and 4 M, respectively) and multiple human leukemia cell lines (IC50s = 1. 7 5. 8 M). Product information CAS Number: 5116 24 5 Molecular Weight: 258. 23 Formula: C10H14N2O6 Synonym: 5 Hydroxymethyl 2' deoxyuridine
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