GDC-0623 udine InChiKey: IHWFKDWIUSZLCJ-UHFFFAOYSA-M

InChiKey: IHWFKDWIUSZLCJ-UHFFFAOYSA-M

treatment with 0

Formula: C24H30F2O6

CH4O3S/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34

Formula: C13H12ClN3O2

GDC-0623 udine InChiKey: IHWFKDWIUSZLCJ-UHFFFAOYSA-MGDC 0623, also known as G 868, is an orally active, selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor GDC 0623 specifically inhibits mitogen activated protein kinase kinase (MEK or MAP ERK kinase), resulting in inhibition of growth factor mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS RAF MEK ERK signaling pathway that regulates cell growth; constitutive activation of this pathway