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with IC50s of 29 and 803 nM for JAK1 and JAK2
Smiles: COC1=CC2=C(C=C1OCCCOC1=CC3N=C[C@@H]4CC(=C)CN4C(=O)C=3C=C1OC)N=C[C@@H]1CC(=C)CN1C2=O
24(32)33)10-9-25(22
LY364947 (< 20 μM) suppresses leukaemia-initiating cells colony-forming ability after co-culture with OP-9 stromal cells
without compromising DNA binding
ACH-000143 y Desipramine-d3 with IC50s of 29 andACH 000143 is a potent and orally active melatonin receptor agonist, with EC50 values of 0. 06 nM and 0. 32 nM for MT1 and MT2, respectively. Product information CAS Number: 2225836 30 4 Molecular Weight: 297. 74 Formula: C13H16ClN3O3 Chemical Name: N [2 (5 chloro 2,6 dimethoxy 1H 1,3 benzodiazol 1 yl)ethyl]acetamide Smiles: CC(=O)NCCN1C(=NC2=CC(Cl)=C(C=C12)OC)OC InChiKey: BVSLRGAPRGQWNC UHFFFAOYSA N InChi: InChI=1S C13H16ClN3O3 c1 8(18)15 4 5 17 11 7