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ZM-447439 time- and dose-dependently inhibits the growth of all three cell lines with IC50 values of 3 μM (BON)
β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels
Mv1Lu cells) treatment efficiently prevents the growth-inhibitory effects of TGF-β
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
the volume of distribution (V(ss)) is moderate: 0
Chrysophanol Size:10mg solid ZM-447439 time- and dose-dependently inhibitsChrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF induced phosphorylation of EGFR and suppresses activation of AKT and mTOR p70S6K. Product information CAS Number: 481 74 3 Molecular Weight: 254. 24 Formula: C15H10O4 Synonym: Chrysophanic acid Chemical Name: 1, 8 dihydroxy 3 methyl 9, 10 dihydroanthracene 9, 10 dione Smiles: CC1C=C(O)C2=C(C=1)C(=O)C1C=CC=C(O)C=1C2=O InChiKey: LQGUBLBATBMXHT UHFFFAOYSA N InChi: InChI=1S
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