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Regorafenib Catalog No.:M10913-10 C4H6O4/c1-17(20-14-13-19(2)3

SKU: 50304567011

4.3
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Description

C4H6O4/c1-17(20-14-13-19(2)3

Smiles: OC(=O)CCC1=C(NC2=CC(Cl)=CC(Cl)=C12)C(O)=O

AZM475271 suppresses tumor growth and metastasis in vitro and in vivo potentially by anti-angiogenic mechanisms

Formula: C16H14O6

Lauridsen JB

Regorafenib Catalog No.:M10913-10 C4H6O4/c1-17(20-14-13-19(2)3Regorafenib, also known as BAY 73 4506 ; is a n orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. Regorafenib demonstrated to increase the overall survival of patients with metastatic

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