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ClH/c1-12-22-23-17(28-12)11-21-9-10-25-19(26)14-6-4-5-13-16(24(2)3)8-7-15(18(13)14)20(25)27
N#CC1CCCN1C(=O)CNCCNC1C=CC(=CN=1)C#N
5)69(90(68)73(65)95)72(94)83-63-15-10-12-53-44-58(25-27-62(53)63)100-42-11-16-67(91)89-40-34-86(35-41-89)33-30-56(49-102-59-13-8-7-9-14-59)82-64-28-26-60(45-66(64)103(96
Epub 2015 Nov 22
PF 06447475
25-Hydroxycholesterol l-JNJ-7706621 ClH/c1-12-22-23-17(28-12)11-21-9-10-25-19(26)14-6-4-5-13-16(24(2)3)8-7-15(18(13)14)20(25)2725 Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll like receptor (TLR) activation. 25 hydroxycholesterol is a potent (EC5065 nM) and selective suppressor of IgA production by B cells. Product information CAS Number: 2140 46 7 Molecular Weight: 402. 65 Formula: C27H46O2 Chemical Name: (1R,3aS,3bS,7S,9aR,9bS,11aR) 1 [(2R) 6 hydroxy 6 methylheptan 2 yl] 9a,11a dimethyl
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