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LDN-214117 inhibited ALK2 most
40 times more effective in inducing cardiogenesis than recombinant Wnt inhibitor protein Dkk)
selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM
10(4):298-304
InChi: InChI=1S/C17H21N3O/c1-19(2)16-10-8-13(9-11-16)14-6-5-7-15(12-14)18-17(21)20(3)4/h5-12H
WAY-316606 hydrochloride - Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor. CAS# 1781835-02-6 60033 LDN-214117 inhibited ALK2 mostWAY 316606, CAS No. 1781835 02 6, is a novel potent and selective inhibitor of secreted frizzled related protein 1 (sFRP 1) with an IC50 ~ 0. 65 M. WAY 316606 prevents sFRP 1 from interacting with Wnt and thus increases Wnt signaling. WAY 316606 can increase total bone area in a murine calvarial organ culture assay. Product information CAS Number: 1781835 02 6 Molecular Weight: 484. 94 Formula: C18H20ClF3N2O4S2 Related CAS Number: 915759 45 4 (free
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