TAK-915 melittoside 3-benzotriazol-2-yl)-2-hydroxy-5-(2

3-benzotriazol-2-yl)-2-hydroxy-5-(2

female athymic nude mice) treatment significantly reduces the tumor progression

5 and 5 μM) specifically induces acetylation of α-tubulin in MM cells

InChi: InChI=1S/C27H44O3/c1-18-8-12-22(28)17-21(18)11-10-20-7-6-16-27(5)23(13-14-24(20)27)19(2)9-15-25(29)26(3

VU0463271 is found to be a moderate-to-high clearance compound in rat (CL=57 mL/min/kg) following intravenous administration (1 mg/kg)

TAK-915 melittoside 3-benzotriazol-2-yl)-2-hydroxy-5-(2TAK 915 is a potent, selective, brain penetrant and orally active phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 0. 61 nM. TAK 915 is >4100 fold more selectivity for PDE2A than PDE1A. TAK 915 has the potential for neuropsychiatric and neurodegenerative disorders treatment. Product information CAS Number: 1476727 50 0 Molecular Weight: 458. 36 Formula: C19H18F4N4O5 Chemical Name: N [(1S) 1 [3 fluoro 4 (trifluoromethoxy)phenyl] 2 methoxyethyl] 7