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AS 1892802 inhibited ROCK1 and ROCK2 with IC50 values of 1
BGJ-398 (ranging between 1 nM and 10 μM) is potent at inhibiting cell growth of FGFR2-mutant endometrial cancer cells
S-4-nitrophenylmethyl-6-thioinosine
Smiles: O=C(CCOCCN1C(=O)C=CC1=O)N1CCN(CC1)C1C=CC(=CC=1)C(=O)NCC1=CC=C(C=C1F)NC(=O)[C@H]1C[C@@H]1C1=CN=CC=C1
It has at least 60-fold selectivity as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members such as KDM3A
Eudesmol stoyl-sn-glycero-3-phosphocholine AS 1892802 inhibited ROCK1 andEudesmol is a sesquiterpenoid compound produced by Streptomyces tendae. Product information CAS Number: 51317 08 9 Molecular Weight: 222. 37 Formula: C15H26O Chemical Name: 2 [(2R,4aR) 4a,8 dimethyl 1,2,3,4,4a,5,6,7 octahydronaphthalen 2 yl]propan 2 ol Smiles: CC(C)(O)[C@H]1CC2=C(C)CCC[C@]2(C)CC1 InChiKey: WMOPMQRJLLIEJV IUODEOHRSA N InChi: InChI=1S C15H26O c1 11 6 5 8 15(4)9 7 12(10 13(11)15)14(2,3)16 h12,16H,5 10H2,1 4H3 t12 ,15 m1 s1 Technical Data
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