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SB-431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4
) shows a significantly strong antitumor effect in mice bearing M109 cells
6 mg/mLwarmed(24
CCC(NC(C)=O)(P([O-])(O)=O)P([O-])([O-])=O
but has no anxiolytic effects on social investigation
PCNA-I1 Size:Contact [email protected] for quotation SB-431542 is a potent andPCNA I1 is a selective inhibitor of proliferating cell nuclear antigen (PCNA, a potential anticancer target). PCNA I1 selectively binds to PCNA trimers with Kd of ~0. 2 to 0. 4 M. PCNA I1 inhibits the growth of tumor cells of various tissue types with IC50 of ~0. 2 M. PCNA I1 induces DNA damage and apoptosis in both LNCaP and PC 3 cells. PCNA I1 also induces autophagy in PC 3 cells. Product information CAS Number: 444930 42 1 Molecular Weight: 310. 37
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