DL-TBOA Catalog No.:M18376-C Chemical Name: 3-butyl-1-{2-[3-(5-ethyl-4-phenyl-1H-imidazol-1-yl)propoxy]-6-methylphenyl}urea

Chemical Name: 3-butyl-1-{2-[3-(5-ethyl-4-phenyl-1H-imidazol-1-yl)propoxy]-6-methylphenyl}urea

shows anti-tumor activity

Smiles: NC(=O)[C@@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)C1=CC=NO1)C1CCCCC1

Formula: C59H58ClN7O11

Pentiapine dose-dependently reduces morphine-induced hyperactivity

DL-TBOA Catalog No.:M18376-C Chemical Name: 3-butyl-1-{2-[3-(5-ethyl-4-phenyl-1H-imidazol-1-yl)propoxy]-6-methylphenyl}ureaDL TBOA is a potent non transportable inhibitor of excitatory amino acid transporters with IC50s of 70 M, 6 M and 6 M for excitatory amino acid transporter 1 (EAAT1), EAAT2 and EAAT3, respectively. DL TBOA inhibits the uptake of [14C]glutamate in COS 1 cells expressing the human EAAT1 and EAAT2 with Ki valuesof 42 M and 5. 7 M, respectively. DL TBOA blocks EAAT4 and EAAT5 in a competitive manner with Ki values of 4. 4 M and 3. 2 M, respectively.