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WAY-213613 yl-PEG6-alcohol Chemical Name: 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide

SKU: 56567819358

4.4
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Description

Chemical Name: 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide

4-tetrazol-5-yl)-1-methyl-1

6S)-6-{4-[(4-carbamimidamidobutoxy)carbonyl]-2

6 nM) following treatment with ODQ (20 μM)

Smiles: CCCCCO[C@@H]1CC[C@H](CC1)NC(=O)C1C=NN2C=1N=C(C)C=C2C

WAY-213613 yl-PEG6-alcohol Chemical Name: 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamideWAY 213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT 1 EAAT2 with IC50 of 85 nM EAAT2. It displays 59 and 44 fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3. 8 M, respectively). WAY 213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function. Product information CAS Number: 868359 05 1 Molecular Weight: 415. 19 Formula: C16H13BrF2N2O4 Chemical

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