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3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide
A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation
Chemical Name: N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide
981 μM consistent with its selectivity for PI3Kβ over PI3Kα
LDC000067 reproduced effects characteristic of CDK9 inhibition such as enhanced pausing of RNA polymerase II on genes and
Valbenazine 582aleplon 3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamideValbenazine (NBI 98854) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110 190 nM. Product information CAS Number: 1025504 45 3 Molecular Weight: 418. 57 Formula: C24H38N2O4 Chemical Name: (2R,3R,11bR) 9,10 dimethoxy 3 (2 methylpropyl) 1H,2H,3H,4H,6H,7H,11bH pyrido[2,1 a]isoquinolin 2 yl (2S) 2 amino 3 methylbutanoate Smiles: COC1C=C2[C@H]3C[C@@H](OC(=O)[C@@H](N)C(C)C)[C@H](CC(C)C)CN3CCC2=CC=1OC InChiKey: GEJDGVNQKABXKG
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