No effect in locomotor activity in the open-field test is observed: (KN-62 treatment [F(1
InChi: InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H
ClH/c26-6-7-33-8-9-34-10-11-35-12-13-36-14-15-37-16-17-38-20-3-1-2-18-22(20)25(32)28(24(18)31)19-4-5-21(29)27-23(19)30
Both Orai1 and TRPC1 are Involved in Excessive Store-Operated Calcium Entry in Striatal Neurons Expressing Mutant Huntingtin Exon 1
or H1152 when inject together with cholera toxin into the loop
PKI(5-24) TFA Catalog No.:M11748-2 No effect in locomotor activityPKI(5 24) TFA is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP dependent protein kinase), with a Ki of 2. 3 nM. PKI(5 24) TFA corresponds to residues 5 24 in the naturally occurring heat stable protein kinase inhibitor. Product information Molecular Weight: 2336. 40 Formula: C96H149F3N32O33 Chemical Name: (2S, 5S, 8S, 11S, 14S, 17S, 20S, 26S, 29S, 35S, 38S, 41S, 44S, 47S) 5 ((1H imidazol 4 yl)methyl) 14 (2 amino 2 oxoethyl) 47