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to BRPF2 with a KD of 500 nM (ITC) and to BRPF3 with a KD of 2
The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity
Epub 2016 Jan 8
Smiles: CC(C)[C@H]1CC2=CC(OCCCOC)=C(C=C2C2=CC(=O)C(=CN21)C(O)=O)OC
DUN09716 (0-100 μM) shows strong inhibition selectivity in NSCLC cells with IC50s ranging from 39
R243 60005 to BRPF2 with a KDR243 is an inhibitor of Chemokine (C C motif) receptor 8 (CCR8) signaling and chemotaxis. Product information CAS Number: 688352 84 3 Molecular Weight: 357. 44 Formula: C21H27NO4 Chemical Name: 7,8 Dihydro 7 [2 (tricyclo[3. 3. 1. 1(3,7)]dec 1 yloxy)ethyl] 6H 1,3 dioxolo[4,5 g][1,3]benzoxazine Smiles: C1C2=CC3OCOC=3C=C2OCN1CCOC12CC3CC(C1)CC(C2)C3 InChiKey: JJMLDSFDOODCIR UHFFFAOYSA N InChi: InChI=1S C21H27NO4 c1(2 26 21 8 14 3 15(9 21)5 16(4 14)10
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