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including improved in vitro activity against Streptococcus pneumoniae
20-72 hours) treatment causes a G0/G1 phase block as well as apoptosis
3-c]furan-4(9H)-one
the cells demonstrate increased levels of labile iron that results in significantly increased clonogenic cell killing
Formula: C19H17F6N3O
Hck-IN-1 Size:Contact [email protected] for quotation including improved in vitro activityHck IN 1 (compound B9), a diphenylpyrazolo compound, is a selective Nef dependent Hck inhibitor with IC50s of 2. 8 M, >20 M for Nef: Hck complex and Hck, respectively. Hck IN 1 is a direct and wide HIV 1 Nef antagonists with an IC50 of 100 300 nM for wild type HIV 1 replication. Hck IN 1 binds pocket residue Asn126 and has anti retroviral activity. Product information CAS Number: 1473404 51 1 Molecular Weight: 402. 81 Formula: C16H11ClN6O3S Chemical
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