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TAM-IN-2 3420 Chemical Name: N-[5-(3-benzenesulfonamidophenyl)-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide

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Description

Chemical Name: N-[5-(3-benzenesulfonamidophenyl)-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide

Structure-activity relationships in a series of substituted indolocarbazoles: Topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties J

InChi: InChI=1S/C17H13FN4O3S/c18-16-7-6-12(13-8-9-19-20-11-13)10-15(16)17(23)21-22-26(24

8 (5-HT5B)

Cholesterol biosynthesis is reduced by 74% (the time for 50% inhibition is ~7 hr)

TAM-IN-2 3420 Chemical Name: N-[5-(3-benzenesulfonamidophenyl)-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamideTAM IN 2 is a TAM inhibitor extracted from patent US 20170275290 A1, pyrrolotriazine compound 0904. Product information CAS Number: 2135642 56 5 Molecular Weight: 583. 59 Formula: C31H27F2N7O3 Chemical Name: N {4 [7 (1 acetylpiperidin 4 yl) 4 aminopyrrolo[2,1 f][1,2,4]triazin 5 yl] 3 fluorophenyl} 1 (4 fluorophenyl) 2 oxo 1,2 dihydropyridine 3 carboxamide Smiles: CC(=O)N1CCC(CC1)C1=CC(=C2C(N)=NC=NN12)C1=CC=C(C=C1F)NC(=O)C1=CC=CN(C2C=CC(F)=CC=2)C1=O

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