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MM-589 TFA Catalog No.:M27742-C H3B-120 achieves inhibition by binding

SKU: 60123729721

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Description

H3B-120 achieves inhibition by binding to an allosteric pocket situated between the integrating and ATP A domains

InChiKey: OFPXSFXSNFPTHF-AREBVXNXSA-N

7 µM) and much weaker inhibition of dopamine reuptake (IC50 >10 µM)

belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I

and phosphorylated Smad3 in keloid fibroblasts

MM-589 TFA Catalog No.:M27742-C H3B-120 achieves inhibition by bindingMM 589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein protein interaction. MM 589 binds to WDR5 with an IC50 of 0. 90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC50 of 12. 7 nM. Product information CAS Number: 2097887 21 1 Molecular Weight: 686. 72 Formula: C30H45F3N8O7 Chemical Name: N [(3R,6S,9S,12R) 6 ethyl 12 methyl 9 [3 (N'' methylcarbamimidamido)propyl] 2,5,8,11 tetraoxo 3

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