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Sacubitril/Valsartan: Updates and Clinical Evidence for a Disease-Modifying Approach
52)53)58-37-11-9-8-10-35(37)46(66)54-6/h8-17
5 nM and 2
de Oliveira CC
InChi: InChI=1S/C18H19N3O3/c1-19-17(23)15-9-13(16(22)20-14-7-8-14)11-21(18(15)24)10-12-5-3-2-4-6-12/h2-6
FIT-039 Catalog No.:M25031-C Sacubitril/Valsartan: Updates and Clinical EvidenceFIT 039 is a selective, ATP competitive and orally active CDK9 inhibitor with an IC50 of 5. 8 M for CKD9 cyclin T1. FIT 039 does not inhibit other CDKs and other kinases. FIT 039 inhibits replication of HSV 1 (IC50 of 0. 69 M), HSV 2, human adenovirus, and human CMV. FIT 039 is a promising antiviral agent for inhibiting drug resistant HSVs and other DNA viruses. Product information CAS Number: 1113044 49 7 Molecular Weight: 315. 41 Formula: C17H18FN3S
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