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Chemical Name: (6S)-5
CYM-5520 also increases osteoblast number
with 50 nM PU-H71 needed to significantly reduce the LPS dependent nitrite release
Smiles: N=C1CCCN1CC1NC(=O)NC(=O)C=1Cl
QCA570 is a potent BET degrader based on PROTAC
(S)-Lisofylline Catalog No.:M22422-C Chemical Name: (6S)-5Lisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,