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26-10-5-3-6-11-26)27-12-7-4-8-13-27
11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]acetamido}ethane-1-sulfonate
[Epub ahead of print] PubMed PMID: 25525863
TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer
Molecular Weight: 157
Salinosporamide A (NPI-0052) Catalog No.:M7476-10 26-10-5-3-6-11-26)27-12-7-4-8-13-27Salinosporamide A (NPI 0052, ML858, Marizomib, MRZ) is a novel marine derived proteasome inhibitor which inhibits CT L 5, C L 1, and T L 2 proteasome activities in human erythrocyte derived 20S proteasomes with IC50 of 3. 5 nM, 430 nM, 28 nM. Product information CAS Number: 437742 34 2 Molecular Weight: 313. 78 Formula: C15H20ClNO4 Synonym: ML858 Marizomib MRZ Chemical Name: (1R,4R,5S) 4 (2 chloroethyl) 1 ((S) ((S) cyclohex 2 en 1 yl)(hydroxy)methyl)
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