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Smiles: NC1N=CN=C2C=1C(=CN2C1CCCC1)C1C=CC(=CC=1)OC1C=CC=CC=1
Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology
also known as SB-220453
with IC50 values of 26
Smiles: CCCCC1C(=O)N(C2CCCCC2)C(=O)NC1=O
TyK2-IN-2 aminomethyl Smiles: NC1N=CN=C2C=1C(=CN2C1CCCC1)C1C=CC(=CC=1)OC1C=CC=CC=1TyK2 IN 2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0. 1 M and 0. 05 M for TYK2 JH2, IL 23 and IFN, respectively. TyK2 IN 2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2 IN 2 can be used for the research of inflammatory and autoimmune diseases. Product information CAS Number: 2098466 94 3 Molecular Weight: 310. 35 Formula: C16H18N6O Chemical Name: 6 [(3,5 dimethylphenyl)amino] 8
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