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12-trihydroxy-7-methoxy-6
The pharmacokinetic behavior and the preclinical antitumor activity in nude mice bearing C6 rat glial tumors indicate that 31 has the potential to become an antiangiogenic agent in the clinic
Zyflo sodium
Formula: C23H17FN6O2
Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis
AV-412 - CAS# 451493-31-5 Catalog No.:M10577-10 12-trihydroxy-7-methoxy-6AV 412, also known as MP 412, is a second generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR HER2 inhibitor AV 412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR HER2 expressing tumors. This agent may be active against EGFR HER2
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