BMS-794833 - CAS# 1174046-72-0 itor 1 (R enantiomer hydrochloride) 53(6):849-54

53(6):849-54

GW-7647 (50 nM) enhances the initial phase of Ca2+-regulated exocytotic events stimulated by ACh in antral mucous cells

CAS Number: 3326-34-9

but only kill cells with MLL rearrangement

in the lateral geniculate nucleus

BMS-794833 - CAS# 1174046-72-0 itor 1 (R enantiomer hydrochloride) 53(6):849-54BMS 794833 is a potent ATP competitive inhibitor of Met VEGFR2 with IC50 of 1. 7 nM 15 nM. BMS 794833 also inhibits Ron (Met family), Axl (phylogenetically related Axl Tyro3 Mer subfamily) and Flt 3 with IC50 values less than 3 nM. The compound was selective versus a panel of greater than 200 additional receptor tyrosine kinase (RTKs), non RTKs and serine threonine kinases based on biochemical or Ambit binding assays. Moreover, it inhibited the cell